Test combinations of kernels and estimators for coordinate-based meta-analyses.

Collection of NIDM-Results packs downloaded from Neurovault collection 1425, uploaded by Dr. Camille Maumet.

Note

Creation of the Dataset from the NIDM-Results packs was done with custom code. The Results packs for collection 1425 are not completely NIDM-Results-compliant, so the nidmresults library could not be used to facilitate data extraction.

import os

from nilearn.plotting import plot_stat_map

import nimare
from nimare.tests.utils import get_test_data_path

Load Dataset

dset_file = os.path.join(get_test_data_path(), "nidm_pain_dset.json")
dset = nimare.dataset.Dataset(dset_file)

mask_img = dset.masker.mask_img

List possible kernel transformers

MKDA density analysis

for kt_name, kt in kernel_transformers.items():
    try:
        mkda = nimare.meta.MKDADensity(kernel_transformer=kt, null_method="approximate")
        mkda.fit(dset)
        corr = nimare.correct.FWECorrector(method="montecarlo", n_iters=10, n_cores=1)
        cres = corr.transform(mkda.results)
        plot_stat_map(
            cres.get_map("logp_level-voxel_corr-FWE_method-montecarlo"),
            cut_coords=[0, 0, -8],
            draw_cross=False,
            cmap="RdBu_r",
            title="MKDA estimator with %s" % kt_name,
        )

    except AttributeError:
        print(
            "\nError: the %s does not currently work with the MKDA meta-analysis method\n"
            % kt_name
        )
  • plot cbma combine estimators and kernels
  • plot cbma combine estimators and kernels
  • plot cbma combine estimators and kernels

Out:

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MKDA Chi2

for kt_name, kt in kernel_transformers.items():
    try:
        mkda = nimare.meta.MKDAChi2(kernel_transformer=kt)
        dset1 = dset.slice(dset.ids)
        dset2 = dset.slice(dset.ids)
        mkda.fit(dset1, dset2)
        corr = nimare.correct.FWECorrector(method="montecarlo", n_iters=10, n_cores=1)
        cres = corr.transform(mkda.results)
        plot_stat_map(
            cres.get_map("z_desc-consistency_level-voxel_corr-FWE_method-montecarlo"),
            threshold=1.65,
            cut_coords=[0, 0, -8],
            draw_cross=False,
            cmap="RdBu_r",
            title="MKDA Chi2 estimator with %s" % kt_name,
        )

    except AttributeError:
        print(
            "\nError: the %s does not currently work with the MKDA Chi2 meta-analysis method\n"
            % kt_name
        )
  • plot cbma combine estimators and kernels
  • plot cbma combine estimators and kernels
  • plot cbma combine estimators and kernels

Out:

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/home/docs/checkouts/readthedocs.org/user_builds/nimare/envs/0.0.10/lib/python3.7/site-packages/nilearn/plotting/displays.py:880: UserWarning: empty mask
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/home/docs/checkouts/readthedocs.org/user_builds/nimare/envs/0.0.10/lib/python3.7/site-packages/nilearn/plotting/displays.py:880: UserWarning: empty mask
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/home/docs/checkouts/readthedocs.org/user_builds/nimare/envs/0.0.10/lib/python3.7/site-packages/nilearn/plotting/displays.py:880: UserWarning: empty mask
  get_mask_bounds(new_img_like(img, not_mask, affine))

KDA

for kt_name, kt in kernel_transformers.items():
    try:
        kda = nimare.meta.KDA(kernel_transformer=kt, null_method="approximate")
        kda.fit(dset)
        corr = nimare.correct.FWECorrector(method="montecarlo", n_iters=10, n_cores=1)
        cres = corr.transform(kda.results)
        plot_stat_map(
            cres.get_map("logp_level-voxel_corr-FWE_method-montecarlo"),
            cut_coords=[0, 0, -8],
            draw_cross=False,
            cmap="RdBu_r",
            title="KDA estimator with %s" % kt_name,
        )

    except AttributeError:
        print(
            "\nError: the %s does not currently work with the KDA meta-analysis method\n" % kt_name
        )
  • plot cbma combine estimators and kernels
  • plot cbma combine estimators and kernels
  • plot cbma combine estimators and kernels

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ALE

for kt_name, kt in kernel_transformers.items():
    try:
        ale = nimare.meta.ALE(kernel_transformer=kt, null_method="approximate")
        ale.fit(dset)
        corr = nimare.correct.FWECorrector(method="montecarlo", n_iters=10, n_cores=1)
        cres = corr.transform(ale.results)
        plot_stat_map(
            cres.get_map("logp_level-cluster_corr-FWE_method-montecarlo"),
            cut_coords=[0, 0, -8],
            draw_cross=False,
            cmap="RdBu_r",
            title="ALE estimator with %s" % kt_name,
        )

    except AttributeError:
        print(
            "\nError: the %s does not currently work with the ALE meta-analysis method\n" % kt_name
        )
  • plot cbma combine estimators and kernels
  • plot cbma combine estimators and kernels
  • plot cbma combine estimators and kernels

Out:

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Total running time of the script: ( 1 minutes 43.250 seconds)

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